Mild to Moderate Atopic Dermatitis: A Guide to Therapeutic Selection A specialist shares insights on the management of patients with atopic dermatitis with an emphasis on topical interventions and long-term management

pattern, atopic dermatitis (AD) affects individuals of all ages, although its prevalence is highest in children. While the pathophysiology of AD is not yet fully understood, genetically-based alterations in barrier function have recently been described, leading to enhanced understanding of the need to maintain the barrier function in this skin disorder. In light of these findings, barrier repair and skin moisturization have emerged as important strategies for patient management, in conjunction with the use of standard therapies for atopic dermatitis. These standard therapies include topical steroids and topical calcineurin inhibitors as well as education to prevent flares and control infection. Proper bathing techniques and avoidance of trigger factors are essential components of an atopic dermatitis treatment regimen. Although topical therapies can effectively treat most cases of mild-to-moderate atopic dermatitis, patient management is often challenging. Most patients will require the concomitant use of several topical agents; and the regimen will change along with the natural course of the skin disease. More severe patients may require regimens that include phototherapy or systemic medications. Clinicians must be adept at devising effective regimens, educating patients on their proper use, and tailoring longterm care to the patient/caregiver needs. Mild to Moderate Atopic Dermatitis: A Guide to Therapeutic Selection